Prime Minister Theresa May is set to trigger Article 50 later, formally starting the process of the UK leaving the European Union.
The next two years of negotiations will have far-reaching implications for British businesses and their staff.
The three main areas companies will be watching in the Brexit talks are: migration, customs, and tariffs.
But different firms - often within the same industry - will rank them in different orders of importance.
With so many competing interests, what message is business sending to the government about the Brexit talks?
In many cases, British trade groups said they wanted to hold on to the best possible access to the EU, the UK's biggest trading partner. How far this is possible, though, will be at the crux of the talks.
The prime minister made it clear in January that her plan was for the UK to leave the EU single market and potentially the customs union.
Unless a new trade deal is put in its place, UK companies face tariffs on imports and exports with the EU, tighter customs checks and more controls on EU workers.
Firms need to know as soon as possible about the new trading relationship, says Steven Altmann-Richer, head of EU policy at business lobby group CBI.
If a trade deal isn't possible in the next two years, interim arrangements are essential, he adds.
Firms are not shy of making their views heard by ministers. More than 80% of big businesses are lobbying the government on the Brexit talks, according to a report by law firm Eversheds Sutherland.
But rather than putting some firms ahead of others, ministers must "prioritise what's best for UK business across the board", says Adam Marshall, director general of the British Chambers of Commerce.Read More...
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